The aim of this work in ethnobotany was to study the diversity and the utilization of natural vegetation in daily life of Thai Song Dam tribal village. In this study, 60 species in 34 families were found. The most found families were Apocynaceae (7 species), followed by Lamiaceae (4 species) and Rutaceae (4 species). Common plant species in Thai Song Dam daily life were Eclipta prostrata (L.) L., Colocasia esculenta L. Schott, Wolffia globosa (Roxb.) Hartog & Plas, Crateva adansonii subsp. trifoliata (Roxb.) Jacobs, Cleome gynandra L., Cleome viscosa L., Melientha suavis Pierre., Indigofera tinctoria L., Thyrsostachys siamensis Gamble, Morinda coreia Ham., Citrus lucida (Scheff.) Mabb., and Zanthoxylum rhetsa DC. Each plant species with their family name, scientific name together with local name and the utilization, were described.