Objective: To synthesize and characterize silver nanoparticles from aqueous bark extracts of Mimusops elengi L. and also evaluate the potentially synthesized silver nanoparticles as antimicrobial agents against pathogens.
Methods: The silver nanoparticles were generated using from the bark extracts of Mimusops elengi L. The characterization of synthesized nanoparticles was done by visual colour change, UV – vis spectroscopy, XRD, FTIR, SEM and EDAX. Antimicrobial activity of synthesized silver nanoparticles was tested against human pathogens by well diffusion method.
Results: It was found that aqueous silver ions can be reduced by aqueous bark extracts of Mimusops elengi to generate extremely stable silver nanoparticles in aqueous medium. The results of antimicrobial studies showed good inhibitory effect against Staphylococcus aureus and Bacillus subtilis. The zone of maximum inhibition is Staphylococcus aureus (18mm), Bacillus subtilis (16mm) and least effective against Pseudomonas aeruginosa (10mm). These results suggest that silver nanoparticles can be used as effective growth inhibitors in various microorganisms making them applicable to diverse medical devices and antimicrobial control systems.
Conclusion: It is concluded that the silver nanoparticles synthesized using Mimusops elengi bark extract would be a better antimicrobial effective against various human pathogens.
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